Stephanie Chan Yen San
Associate Prof. Ir. Dr. Stephanie Chan Yen San
PhD, BEng (Hons), PEng, CPEng, MIEAust, NER, FHEA
Head of Chemical Engineering Department
Associate Professor
Contact Details
Location: Skylark 3 Room 426
Tel: +60 85 630 100 Ext: 2538
Fax: +60 85 630 254
Email: chanyensan@curtin.edu.my
Google Scholar: https://scholar.google.com/citations?hl=en&user=M2oc75cAAAAJ&view_op=list_works&sortby=pubdate
ResearchGate: https://www.researchgate.net/profile/Yen_San_Stephanie_Chan
SCOPUS: https://www.scopus.com/authid/detail.uri?authorId=57205349238
ORCID: https://orcid.org/0000-0002-4274-0678
Academic History
- Doctor of Philosophy, Universiti Sains Malaysia (2014)
- Bachelor Degree in Engineering (Chemical-Bioprocess), Universiti Teknologi Malaysia (2010)
Awards
- Gold Medal Award, The 3rd World International Innovation iCAN 2018 – Toronto International Society of Innovation and Advanced Skills (TISIAS), 1st September, Toronto, Canada
- Special Award, The 3rd International Invention Innovation Competition in Canada, iCAN 2018, 1st September, Toronto, Canada
- Hyogo Oversea Research Network fellowship, Hyogo Prefecture, 2018
- Young Women Award. Venus International Foundation. Chennai India 3rd March 2018
- Gold medal award. 3rd Word Invention Innovation Contest (WiC) organized by Korea Invention News (KINEWS) and co-organized by iCAN -TORONTO, Canada in Seoul Korea 3-4 June 2017
- Special Honor of Invention. 3rd Word Invention Innovation Contest (WiC) organized by Korea Invention News (KINEWS) and co-organized by iCAN -TORONTO, Canada in Seoul Korea 3-4 June 2017
Research Interest
- Bionanotechnology specifically on bionanomaterials synthesis, nanoformulation
- Biotechnology in relation to agricultural biotechnology
- Bioprocessing of phytomedicine for therapeutic actions
- Chemical engineering
Research Funding & Research Projects
- Funder: Sarawak Research Development Council-Catalyst Fund
Title: Enhancement of antimalarial property of Alpinia galangal extract through nanoemulsion formulation with essential oils of P. nigrum, C. Odontophyllu,, N. sativa, C.domestica and P. betle
Amount: RM198,840
Team members: A/Prof Dr Stephanie Chan Yen San (PI), A/Prof Dr Jobrun Nandong, Freddie Panau, Dr Angela Siner, Dr Jibrail Kansedo
Duration/Status: 2020-2023/On-going - Funder: Sarawak Research Development Council-Catalyst Fund
Title: Magnesium oxide nanoparticles as a potential alternative to copper-based fungicide: The pathogenic capability and transport properties
Amount: RM185,725
Team members: A/Prof Dr Law Ming Chiat (PI), A/Prof Dr Stephanie Chan Yen San, Dr Angnes Tiong Ngieng Tze, Dr Choy Sook Yan, A/Prof Dr King Jie Hung
Duration/Status: 2020-2023/On-going - Funder: Sarawak Research Development Council-Catalyst Initiation
Title: Development of Annas comosus as biosorbent for liquid medical waste
Amount: RM 138,150
Team members: Dr Angela Siner (PI), A/Prof Dr Stephanie Chan Yen San
Duration/Status: 2020-2023/On-going - Funder: Fundamental Research Grant Scheme
Title: Understanding of Mechanisms Affecting the Effectiveness of Magnetic Biochar Catalyst for Biodiesel Production
Amount: RM133,800
Team members: Dr Tan Yie Hua (PI), Dr Jibrail Kansedo, A/Prof Dr Mubarak Mujawar, A/Prof Dr Stephanie Chan Yen San, Prof Mohammad Omar Abdullah
Duration/Status: 2019-2022/On-going - Funder: Fundamental Research Grant Scheme
Title: Mechanism of multistage nano-enabled microbial fermentation of macroalgae to produce high optically pure lactic acid for biodegradable polymer
Amount: RM132,080
Team members: Dr Tan Inn Shi (PI), Dr Henry Foo Chee Yew, A/Prof Dr Stephanie Chan Yen San, A/Prof Dr Leo Choe Peng
Duration/Status: 2019-2022/On-going - Funder: Xiamen University Malaysia
Title: Life Cycle Evaluation of Food Waste Management System for Energy Recovery, Environmental Sustainability and Optimized Cost
Amount: RM59,930
Team members: Dr Woon Kok Sin (PI), A/Prof Dr Stephanie Chan Yen San, Prof Lee Chew Tin
Duration/Status: 2019-2021/On-going - Funder: Sarawak Research Development Council-Research Initiation
Title: Pilot plant scale supercritical CO2 extraction of natural antioxidant from Brucea Javanica Seeds used for pharmaceutical applications
Amount: RM50,000
Team members: Dr Tan Inn Shi (PI), A/Prof Dr Stephanie Chan Yen San, Dr Henry Foo Chew Yew, Dr Tan Yie Hua, Freddie Panau, Lam Man Kee
Duration/Status: 2020-2021/On-going - Funder: Curtin Malaysia Teaching Innovation Program 2019
Title: Flipped-delivery and rapid prototyping as blended project- based learning in Fluid Mechanics
Amount: RM2,000
Team members: Dr Tan Inn Shi (PI), Dr Henry Foo Chew Yew, A/Prof Dr John Lau Sie Yon, A/Prof Dr Stephanie Chan Yen San
Duration/Status: 2019-2020/On-going - Funder: MJM (Palm Oil)
Title: Production and Quality Determination of Organic Fertilizer Derived from Oil Palm Decanter Cake.
Amount: RM 10,000
Team members: A/Prof Dr Stephanie Chan Yen San (PI), Ir Tian Foon Howe
Duration/Status: 2016/Completed - Funder: Fundamental Research Grant Scheme
Title: Investigation on shear strength and consolidation behaviour of peat treated using microbial induced calcite precipitation
Amount: RM 91,800
Team members: Dr Wong Kwong Soon (PI), Dr Stephanie Chan Yen San, Dr Lau Sie Yon
Duration/Status: 2015-2019/Completed - Funder: Fundamental Research Grant Scheme
Title: Development, numerical modelling and experimental verification of a microwave-heated and cavitation-induced distillation vessel to improve the cold flow properties of palm oil biodiesel
Amount: RM 122,000
Team members: Dr Law Ming Chiat (PI), Dr Stephanie Chan Yen San, Dr Vincent Lee, Dr Wee Siaw Kur, A/P Dr You Kok Yew, A/P Dr Zulkifly Abbas, Dr Ulugbek Azimov
Duration/Status: 2014-2018/Completed - Funder: Fundamental Research Grant Scheme
Title: Characterization and modelling of oil palm fruits and bunches subject to microwave heating
Amount: RM 94,000
Team members: Dr Stephanie Chan Yen San (PI), Dr Law Ming Chiat, Dr Leo Choe Peng, A/P Dr You Kok Yew, A/P Dr Zulkifly Abbas
Duration/Status: 2014-2018/Completed - Funder: Curtin Sarawak Research Fund
Title: Impregnation of silver nanopartilces in a polysulfone membrane: Filtration performance, antimicrobial ability and biofouling resistance studies
Amount: RM 10,000
Team members: Dr Stephanie Chan Yen San (PI), Ms Lau Shiew Wei, Dr Leo Choe Peng
Duration/Status: 2014/Completed
Selected Publications
A. Book Chapter
- Ling J.K.U., Hii Y.S., Jeevanandam J., Chan Y.S., Danquah M.K. (2019) Nanoencapsulation of Phytochemicals and in-vitro Applications. In: Kumar S., Egbuna C. (eds) Phytochemistry: An in-silico and in-vitro Update. Springer, Singapore
- Jeevanandam J., Chan YS. (2019). Chapter 6: In vitro and In vivo toxicity of metal nanoparticles and their drug delivery applications. Part 1: Therapeutic Potentials of Phytopharmaceutical. In: Goyal MR, Mishra A, Egbuna C. (eds). Essentials of Phytopharmaceuticals, nutraceluticals and Traditional Medicine. Apple Academic Press, CRC Press, USA
- Hii, YS, Jeevanandam J, Chan YS, Danquah MK (2019). Chapter 21: Cytotoxicity and Biomedical Applications of Metal Oxide Nanoparticles Synthesized from Plants. Phytochemistry. In: Egbuna C, Kumar S, Ifemeje JC, Kurhekar JV. (eds). Pharmacognosy, Nanomedicine and Contemporary Issues. Apple Academic Press, CRC Press, USA.
- Nnaji, OC., Jeevanandam, J., Chan, YS, Danquah, MK, Pan, S., Barhoum, A. (2017) Chapter 13: Engineered nanomaterials for wastewater treatment-Current and future trends. Fundamentals of nanoparticles (1st edition) Elsevier.
- Jeevanandam, J., Aing, YS., Chan, YS., Pan, S., Danquah, MK (2016) Chapter 3: Nano-formulation and application of phytochemicals as antimicrobial agents. Antimicrobial nanoarchitectonics (1st Edition): From synthesis to application. Elservier.
- Mat Don, M., Chan, Y. S. and Jeevanandam, J. (2016) Chapter 8: Antimicrobial Properties of Nanobiomaterials and the Mechanicsm. Nanobiomaterials in Antimicrobial Therapy. Applications of Nanobiomaterials Volume 6. 261-312.
B. Journal Publications
- Jeevanandam J, Chan YS, Danquah MK, Law MC (2019). Cytotoxicity analysis of morphologically different sol-gel synthesized MgO nanoparticles and their in vitro insulin resistance reversal ability in adipose cells. Applied Biochemistry and Biotechnology. doi: 10.1007/s12010-019-03166-z
- Tan YH, Abdullah MO, Kansedo J, Mubarak NM, Chan YS, Nolasco-Hipolito C (2019). Biodiesel production from used cooking oil using green solid catalyst derived from calcined fusion waste chicken and fish bones. Renewable Energy 139:696-706
- Chung ZL, Tan YH, Chan YS, Kansedo J, NM Mubarak, Ghasemi M, Abdullah MO (2019). Life cycle assessment of waste cooking oil for biodiesel production using waste chicken eggshell derived CaO as catalyst via transesterification. Biocatalysis and Agricultural Biotechnology. 21. https://doi.org/10.1016/j.bcab.2019.101317
- Wong CW, Chan YS, Jeevanandam, J, Kaushik P, Mikhael B, Elkodous MA, El-Sayyad, G.S. (2019). Response Surface Methodology Optimization of Monodispersed MgO nanoparticles Fabricated by Ultrasonic-assisted sol-gel for outstanding antimicrobial and antibiofilm activities. Journal of Cluster Science. https://doi.org/10.1007/s10876-019-01651-3
- Jeevanandam,J, Chan YS, Danquah MK (2019). Zebrafish as a model organism to study nanomaterial toxicity. Emerging Science Journal. 3(3):195-208.
- Jeevanandam, J, Chan YS, Danquah MK (2019). Effect of Gelling Agent and Calcination Temperature in Sol-Gel Synthesized MgO nanoparticles. Protection of Metals and Physical Chemistry of Surfaces. 55(2):288-301
- Andra S, Balu SK, Jeevanandam J, Muthalagu M, Vidyavathy M, Chan YS, Danquah MK (2019). Photosynthesized metal oxide nanoparticles for pharmaceutical applications. Nauyn-Schmiedeberg’s Achieves of Pharmacology. 392(7):755-771
- Jeevanandam, J, Chan YS, Danquah MK (2019). Effect of pH variations on morphological transformation of biosynthesized MgO nanoparticles. Particulate Science and Technology. DOI: 10.1080/02726351.2019.1566938
- Hii YS, Jeevanandam J, Chan YS (2019). Plant mediated green synthesis and nanoencapsulation of MgO nanoparticles from Calotropis gigantean: Characterisation and kinetic release studies. DOI:10.1080/24701556.2019.1569053
- Yeong, SP, Law MC, You KY, Chan YS, Lee, VC-C (2019) A coupled electromagnetic-thermal-fluid-kinetic model for microwave-assisted production of Palm Fatty Acid Distillate biodiesel. Applied Energy 237:457-475
- Jeevanandan, J. Barhou, A, Chan, YS, Dufresne, A, Danquah, MK. (2018) Review on nanoparticles and nanostructured materials: History, sources, toxicity and regulations. Beilstein Journal of Nanotechnology 9:1050-1074
- Law, MC, Chang, JSL, Chan YS, Pui DY, You KY. (2018). Experimental characterization and modeling of microwave heating of oil palm kernels, mesocarps and empty fruit bunches. Drying Technology. DOI” 10.1080/09373937.2018.1439057
- Jeevanandam, J. Chan, Y.S., Ku, Y.H. (2018). Aqueous Eucalyptus globulus leaf extract-mediated biosynthesis of MgO nanorod. Applied Biological Chemistry. 61 (2) 197-208.
- Phang, RKI, Chan, YS, Wong, KS, Lau, SY (2018). Isolation and characterization of urease-producing bacteria from tropical peat. Biocatalysis and Agricultural Biotechnology. 13:168-175
- Jeevanandam, J., Chan, YS., Danquah, MK (2017). Biosynthesis and characterization of MgO nanoparticles from plant extracts via induced molecular nucleation. New Journal of Chemistry 41: 2800-2814.
- Jeevanandam, J., Chan, YS., Danquah, MK (2017). Calcination-Dependent Morphology Transformation of Sol-Gel Synthesized MgO Nanoparticles. Chemistry Select 2: 10393-10404
- Jessie S.L, Chang, Chan, YS., Law, MC, Leo, CP (2017).Comparative microstructure study of oil palm fruit bunch fibre, mesocarp and kernels after microwave pre-treatment. IOP Conference Series: Materials Science and Engineering 217:012026. (Doi:10.1088/1757-899X/217/1/012026).
- Yeong, SP., Law, MC, Vincent Lee, CC., Chan, YS (2017). Modelling batch microwave heating of water. IOP Conference Series: Materials Science and Engineering 217:012035 (Doi:10.1088/1757-899X/217/1/012035).
- Jeevanandam, J., Chan, Y. S., Danquah., M. K. (2016). Nano-formulation of drugs: recent developments, impact and challenges. Biochimie 128: 99-112.
- A Anand Kumar, J. Jaison, K. Prabakaran, R. Nagarajan, Y. S. Chan (2016). Water Quality Monitoring: A comparative case study of municipal and Curtin Sarawak’s lake samples. IOP Conference Series: Materials Science and Engineering 121:012019. Doi:10.1088/1757-899x/121×1/012019
- Jeevanandam, J., Chan, Y. S., Danquah, M.K. (2016). Biosynthesis of Metal Oxide Nanoparticles. ChemBioEng Reviews. doi: 10.1002/cben.201500018
- M.C., Law, E. L. Liew,. S. L. Chang, Y. S. Chan, C.P. Leo (2016). Modelling microwave heating of discrete samples of oil palm kernels. Applied Thermal Engineering 98:702-726.
- Jeevanandam, J., Danquah, M. K., Debnath, S., Meka, V. S., Chan, Y. S. (2015). Opportunity for nano-formulations in type 2 diabetes mellitus treatments. Current Pharmaceutical Biotechnology 16(10):853-870
- J.S.L. Chang, M.C. Law, Y.S. Chan, C.P. Leo (2015) Effect of Microwave Heating on Oil Palm Mesocarp. Chemical Engineering Transactions. 45:1633-1638
- Jeevanadam, J., Ashok Raja, C., Balakumar, S., Chan, Y. S. (2015). Sol-gel synthesis and characterization of magnesium peroxide nanoparticles. IOP Conference Series: Materials Science and Engineering 78:12005. 1-8.
- Chan, Y.S. and Mashitah, M.D. (2013). Biosynthesis of silver nanoparticles from Schizophyllum commune and in vitro antimicrobial activity studies. Journal of Physical Science 24(2): 83-96.
- Chan, Y.S. and Mashitah, M.D. (2013). Optimization of process variables for the synthesis of silver nanoparticles by Pycnoporus sanguineus using statistical experimental design. Journal of Korean Society for Applied and Biological Chemistry 56(1): 11-20.
- Chan, Y.S. and Mashitah, M.D. (2013). Biosynthesis and structural characterization of Ag nanoparticles from white rot fungi. Materials Science and Engineering C. 33:282-288.
- Chan, Y.S. and Mashitah, M.D. (2013). Optimization of process parameters in bioreduction of Ag nanoparticles by Pycnoporus sanguineus. Advanced Materials Research. 626: 95-98.
- Chan, Y.S. and Mashitah, M.D. (2011). A macro view of Bionanotechnology: Application and implications in the near future. Journal of Bionanoscience. 5:97-106.
- Mashitah, M.D. and Chan, Y. S (2010). Biosynthesis and characterization of silver nanoparticles synthesized by Schizophyllum commune. World Journal of Engineering. Supplement 3: 793.
- Chan, Y.S and Mashitah, M.D. (2010). Synthesis of silver nanoparticles (AgNPs) by Pycnoporous sanguineus. Malaysian Journal of Pharmaceutical Sciences. Supplement 1:5-6.
C. Conference Proceedings
- A Anand Kumar, J. Jaison, K. Prabakaran, R. Nagarajan, Y. S Chan (2015). Water Quality Monitoring: A comparative case study of municipal and Curtin Sarawak’s lake samples. In Proceeding: The 10th CUTSE International Conference, Curtin University Sarawak, 6-7 November 2015.
- Y.S. Chan and M.C. Law (2015). A short review on the implementation of open-ended laboratory towards innovative and creative thinking in engineering discipline. 3rd International Higher Education Teaching and Learning Conference. 26-27 Nov 2015 Curtin University Miri Sarawak
- Anwar, N, Khandoker, S. Islam, S. Debnath, P. Kumar, Y.S. Chan, M.K. Danquah (2015). Class attendance: A key parameter towards quality engineering graduates. 3rd International Higher Education Teaching and Learning Conference. 26-27 Nov 2015 Curtin University Miri Sarawak
- Jessie Sze Ling Chang, Ming Chiat Law, Yen San Chan (2015). Microstructure study on oil palm fruit bunch fibre after microwave drying pre-treatment. In Proceeding: The 3rd Faculty of Engineering Postgraduate Research Colloquium 2015, UNIMAS, Sarawak, 14 April, 2015.
- Jeevanandam, J, Chan, Y. S., Muthiah, S. (2015). Biosynthesis of Gold Nanoparticles by Aspergillus tamarii. In Proceeding: The 3rd Faculty of Engineering Postgraduate Research Colloquium 2015, UNIMAS, Sarawak, 14 April, 2015.
- Jeevanandam, J., Ashok Raja, C., Balakumar, S., Chan, Y. S. (2014). Sol-gel synthesis and characterization of magnesium peroxide nanoparticles. In Proceeding: The 9th CUTSE International Conference, Curtin University Sarawak, 3-5 Dec 2014
- Chan, Y. S, Mashitah, M.D., Lim, J.K. and Mohamed, A.R. (2013). Comparative studies on the synthesis of silver nanoparticles by Pycnoporus sanguineus in shake flasks and stirred tank reactor. In: Proceeding of CHEMECA 2013: Challenging Tomorrow. Brisbane, Queensland. Barton, ACT: Engineers Australia, 39-43.
- Chan, Y.S. and Mashitah, M.D. (2012). Optimization of process parameter in bioreduction of Ag nanoparticles by Pycnoporus sanguineus. In: Proceeding of International Conference on Advanced Material Engineering and Technology (ICAMET 2012). Bayview Beach Resort, Penang, Malaysia, 28-30 November 2012.
- Othman, N.Z, Chan, Y. S., Malek, R.A., Ramli, S., Ismail, N.S., Sarmidi, M.R., Aziz, R., El-Enshasy, H.A. (2012). Bioprocess optimization for cell mass production and functional characterization of: Lactobacillus plantarum. In: Proceeding of 2012 AIChE Annual Meeting, AlChE2012, Pittsburgh, PA, 28 October -2 November 2012.
- Chan, Y. S. And Mashitah, M. D. (2011). Biosynthesis of silver nanoparticles from Schizophyllum commune and in vitro antimicrobial activity studies. In Proceeding of The 18thRegional Symposium on Chemical Engineering (RSCE2011). Ho Chi Minh, Vietnam, 27-28 October 2011,
- Mashitah, M.D. and Chan, Y. S (2011). Schizophyllum commune as nano-factory for biosynthesis of silver nanoparticles. In Proceeding of The Nineteenth Annual International Conference on Composites/Nano Engineering (ICCE-19). Shanghai, China, 24-30 July 2011.
- Chan, Y. S. And Mashitah, M. D. (2011). Instantaneous biosynthesis of silver nanoparticles by selected macro fungi. In: Proceeding of the 2ndInternational Conference on Biotechnology Engineering, The Legend Hotel Kuala Lumpur, Malaysia, 17-19 May 2011. ISBN: 978-983-42978-3-1.
- Chan, Y.S. and Mashitah, M.D (2010). Synthesis of silver nanoparticles (AgNPs) by Pycnoporous sanguineus. In: Proceeding of International Conference on Natural Products, Bayview Beach Resort, Penang, Malaysia, 10-12 December 2010.
- Chan, Y.S., El-Enshasy H., Othman, N. Z., Malek, R.A. Bioprocess optimization and functionality characterization of Lactobacillus plantarum. In: Proceeding of the 3rd International Conference of Biotechnology and Wellness Industry. Putra World Trade Center, Kuala Lumpur, Malaysia, 8-10 October 2010
HDRs Supervision
- HDR Student Name: Hii Yiik Siang
Supervisors: Dr Stephanie Chan, Dr Lau Shiew Wei, Prof Michael Danquah
Project: Isolation and microencapsulation of phosphate solubilizing microorganisms for enhanced agricultural growth on peat.
Status: On-going (PhD) - HDR Student Name : Jordy Ling Kim Ung
Supervisors: Dr Stephanie Chan, A/P Dr Jobrun Nandog, Dr Yalun Arrifin
Project: Antioxidant nanoemulsion formulation from the extract of Mangifera panjang
Status: On-going (PhD) - HDR Student Name : Jessie Chang Sze Ling
Supervisors: A/P Dr Chua Han Bing, Dr Law Ming Chiat, Dr Stephanie Chan Yen San
Project Title: Modeling microwave heating of oil palm fruits and bunches
Status: Completed (MSc) - HDR Student Name: Jaison Jevanandam
Supervisors: Professor Dr Michael Danquah, Dr Stephanie Chan Yen San, A/P Dr Sujan Debnath, Dr Srinkath Vekata
Project: Enhanced synthesis and delivery of MgO nanoparticles for reverse insulin resistance in Type 2 Diabetes
Status: Completed (PhD) - HDR Student Name: Ivy Yii Siew Aing
Supervisors: Professor Dr Michael Danquah, Dr Stephanie Chan Yen San Chan
Project: Pressurized solvent-free microwave extraction of garlic oil
Status: Completed (MSc) - HDR Student Name: Yeong Siew Ping
Supervisors: Dr Law Ming Chiat, Dr Stephanie Chan Yen San, Dr Vincent Lee Chieng Chen
Project: Development, modelling and experimental verification of a amicrowave-heated, cavitation-induced distillation vessel to improve the cold-flow properties of palm oil biodiesel
Status: On-going (PhD) - HDR Student Name: Tan Kei Xian
Supervisors: Professor Dr Michael Danquah, Dr Stephanie Chan Yen San, Dr John Lau Sie Yon
Project: Aptameric Formulation for Enhanced Cell-targeted Drug Delivery
Status: Completed (PhD) - HDR Student Name: Ignatius Phang
Supervisors: Dr Wong Kwong Soon, Dr Stephanie Chan Yen San, Dr John Lau Sie Yon
Project: Investigation on shear strength and consolidation behavior of peat treated using microbial induced calcite precipitation
Status: On-going (PhD)
Professional Associations
- Professional Engineer, Board of Engineers Malaysia (since 2020)
- Sarawak Activity Director, American Chemistry Society Malaysia Chapter 2018-2020
- CPEng, MIEAust (member of Engineers Australia, 2017)
- Vice Chairman II, Young Engineer Section – Institution of Engineers Malaysia 2017-2018
- Institutional Representative of American Chemistry Society Malaysia, 2015
- Committee member of IEM-YES Miri and Editor for IEM Miri’s Newsletter, 2015
- Graduate Member, Institution of Engineers Malaysia, 2013
- Graduate Member, Board of Engineers Malaysia, 2010
- Member, Golden Key International Honor Society, 2008